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Promising Combination Therapy with Bevacizumab and Erlotinib in an EGFR-Mutated NSCLC Patient with MET Amplification Who Showed Intrinsic Resistance to Initial EGFR-TKI Therapy
In lung cancer, several potential mechanisms of intrinsic and acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been explored, including mesenchymal-epithelial transition factor (MET) signaling pathway activation. On the other hand, vascular endoth...
Autores principales: | Seki, Nobuhiko, Natsume, Maika, Ochiai, Ryosuke, Haruyama, Terunobu, Ishihara, Masashi, Fukasawa, Yoko, Sakamoto, Takahiko, Tanzawa, Shigeru, Usui, Ryo, Honda, Takeshi, Ota, Shuji, Ichikawa, Yasuko, Watanabe, Kiyotaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381877/ https://www.ncbi.nlm.nih.gov/pubmed/30792648 http://dx.doi.org/10.1159/000493088 |
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