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Effective implementation of the Accelerate Pheno™ system for positive blood cultures

Using conventional methods, organism identification (ID) and antibiotic susceptibility testing (AST) results are available ∼1.5–3 days after positive blood culture. New technologies can reduce this time to 8–12 h, allowing therapy to be optimized substantially sooner. To make full use of fast ID and...

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Detalles Bibliográficos
Autores principales: Humphries, Romney, Di Martino, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382030/
https://www.ncbi.nlm.nih.gov/pubmed/30690541
http://dx.doi.org/10.1093/jac/dky534
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author Humphries, Romney
Di Martino, Tiziana
author_facet Humphries, Romney
Di Martino, Tiziana
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description Using conventional methods, organism identification (ID) and antibiotic susceptibility testing (AST) results are available ∼1.5–3 days after positive blood culture. New technologies can reduce this time to 8–12 h, allowing therapy to be optimized substantially sooner. To make full use of fast ID and AST results requires overcoming various hurdles to effective implementation, including restructuring laboratory workflows to optimize timeliness of results and modifying clinical pathways to respond more quickly when results are available. Efficient laboratory procedures and clinical interventions coupled with fast and accurate identification and AST results have the potential to substantially reduce overall costs and provide more-sophisticated and effective patient management.
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spelling pubmed-63820302019-02-25 Effective implementation of the Accelerate Pheno™ system for positive blood cultures Humphries, Romney Di Martino, Tiziana J Antimicrob Chemother Supplement Papers Using conventional methods, organism identification (ID) and antibiotic susceptibility testing (AST) results are available ∼1.5–3 days after positive blood culture. New technologies can reduce this time to 8–12 h, allowing therapy to be optimized substantially sooner. To make full use of fast ID and AST results requires overcoming various hurdles to effective implementation, including restructuring laboratory workflows to optimize timeliness of results and modifying clinical pathways to respond more quickly when results are available. Efficient laboratory procedures and clinical interventions coupled with fast and accurate identification and AST results have the potential to substantially reduce overall costs and provide more-sophisticated and effective patient management. Oxford University Press 2019-01 2019-01-25 /pmc/articles/PMC6382030/ /pubmed/30690541 http://dx.doi.org/10.1093/jac/dky534 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Supplement Papers
Humphries, Romney
Di Martino, Tiziana
Effective implementation of the Accelerate Pheno™ system for positive blood cultures
title Effective implementation of the Accelerate Pheno™ system for positive blood cultures
title_full Effective implementation of the Accelerate Pheno™ system for positive blood cultures
title_fullStr Effective implementation of the Accelerate Pheno™ system for positive blood cultures
title_full_unstemmed Effective implementation of the Accelerate Pheno™ system for positive blood cultures
title_short Effective implementation of the Accelerate Pheno™ system for positive blood cultures
title_sort effective implementation of the accelerate pheno™ system for positive blood cultures
topic Supplement Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382030/
https://www.ncbi.nlm.nih.gov/pubmed/30690541
http://dx.doi.org/10.1093/jac/dky534
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