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Effective implementation of the Accelerate Pheno™ system for positive blood cultures
Using conventional methods, organism identification (ID) and antibiotic susceptibility testing (AST) results are available ∼1.5–3 days after positive blood culture. New technologies can reduce this time to 8–12 h, allowing therapy to be optimized substantially sooner. To make full use of fast ID and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382030/ https://www.ncbi.nlm.nih.gov/pubmed/30690541 http://dx.doi.org/10.1093/jac/dky534 |
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author | Humphries, Romney Di Martino, Tiziana |
author_facet | Humphries, Romney Di Martino, Tiziana |
author_sort | Humphries, Romney |
collection | PubMed |
description | Using conventional methods, organism identification (ID) and antibiotic susceptibility testing (AST) results are available ∼1.5–3 days after positive blood culture. New technologies can reduce this time to 8–12 h, allowing therapy to be optimized substantially sooner. To make full use of fast ID and AST results requires overcoming various hurdles to effective implementation, including restructuring laboratory workflows to optimize timeliness of results and modifying clinical pathways to respond more quickly when results are available. Efficient laboratory procedures and clinical interventions coupled with fast and accurate identification and AST results have the potential to substantially reduce overall costs and provide more-sophisticated and effective patient management. |
format | Online Article Text |
id | pubmed-6382030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-63820302019-02-25 Effective implementation of the Accelerate Pheno™ system for positive blood cultures Humphries, Romney Di Martino, Tiziana J Antimicrob Chemother Supplement Papers Using conventional methods, organism identification (ID) and antibiotic susceptibility testing (AST) results are available ∼1.5–3 days after positive blood culture. New technologies can reduce this time to 8–12 h, allowing therapy to be optimized substantially sooner. To make full use of fast ID and AST results requires overcoming various hurdles to effective implementation, including restructuring laboratory workflows to optimize timeliness of results and modifying clinical pathways to respond more quickly when results are available. Efficient laboratory procedures and clinical interventions coupled with fast and accurate identification and AST results have the potential to substantially reduce overall costs and provide more-sophisticated and effective patient management. Oxford University Press 2019-01 2019-01-25 /pmc/articles/PMC6382030/ /pubmed/30690541 http://dx.doi.org/10.1093/jac/dky534 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Supplement Papers Humphries, Romney Di Martino, Tiziana Effective implementation of the Accelerate Pheno™ system for positive blood cultures |
title | Effective implementation of the Accelerate Pheno™ system for positive blood cultures |
title_full | Effective implementation of the Accelerate Pheno™ system for positive blood cultures |
title_fullStr | Effective implementation of the Accelerate Pheno™ system for positive blood cultures |
title_full_unstemmed | Effective implementation of the Accelerate Pheno™ system for positive blood cultures |
title_short | Effective implementation of the Accelerate Pheno™ system for positive blood cultures |
title_sort | effective implementation of the accelerate pheno™ system for positive blood cultures |
topic | Supplement Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382030/ https://www.ncbi.nlm.nih.gov/pubmed/30690541 http://dx.doi.org/10.1093/jac/dky534 |
work_keys_str_mv | AT humphriesromney effectiveimplementationoftheacceleratephenosystemforpositivebloodcultures AT dimartinotiziana effectiveimplementationoftheacceleratephenosystemforpositivebloodcultures |