Chimeric Antigen Receptor–modified T Cells Repressed Solid Tumors and Their Relapse in an Established Patient-derived Colon Carcinoma Xenograft Model

Adoptive transfer of T cells engineered with a chimeric antigen receptor (CAR) is deemed as the silver bullet to overcome the barriers of solid tumor treatment; however, the therapeutic application against solid tumors faces major challenges largely owing to the complex heterogeneity and immunosuppr...

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Detalles Bibliográficos
Autores principales: Teng, Ruidi, Zhao, Jingjing, Zhao, Yiding, Gao, Junshuang, Li, Haibo, Zhou, Shixin, Wang, Yuan, Sun, Qiang, Lin, Zhongqing, Yang, Weifeng, Yin, Ming, Wen, Jinhua, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Basic Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382056/
https://www.ncbi.nlm.nih.gov/pubmed/30586347
http://dx.doi.org/10.1097/CJI.0000000000000251

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