Molecular features of steroid-binding antidins and their use for assaying serum progesterone

Chicken avidin (Avd) and streptavidin from Streptomyces avidinii are extensively used in bionanotechnology due to their extremely tight binding to biotin (K(d) ~ 10(−15) M for chicken Avd). We previously reported engineered Avds known as antidins, which have micro- to nanomolar affinities for steroi...

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Detalles Bibliográficos
Autores principales: Agrawal, Nitin, Lehtonen, Soili I., Uusi-Mäkelä, Meri, Jain, Purvi, Viitala, Sari, Määttä, Juha A. E., Kähkönen, Niklas, Azizi, Latifeh, Riihimäki, Tiina A., Kulomaa, Markku S., Johnson, Mark S., Hytönen, Vesa P., Airenne, Tomi T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382169/
https://www.ncbi.nlm.nih.gov/pubmed/30785944
http://dx.doi.org/10.1371/journal.pone.0212339

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