Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)

An Alzheimer's disease (AD) brain is featured with the oxidative and inflammatory microenvironment caused by overactivated microglia. In article number 1801586, Chen Jiang and co‐workers design a brain normalizing system to eliminate reactive oxygen species (ROS) and reeducate microglia from an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yifei, Guo, Zhongyuan, Zhang, Yujie, Li, Chao, Zhang, Yu, Guo, Qin, Chen, Qinjun, Chen, Xinli, He, Xi, Liu, Lisha, Ruan, Chunhui, Sun, Tao, Ji, Bin, Lu, Weigen, Jiang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Back Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382302/
http://dx.doi.org/10.1002/advs.201970024
_version_ 1783396646667681792
author Lu, Yifei
Guo, Zhongyuan
Zhang, Yujie
Li, Chao
Zhang, Yu
Guo, Qin
Chen, Qinjun
Chen, Xinli
He, Xi
Liu, Lisha
Ruan, Chunhui
Sun, Tao
Ji, Bin
Lu, Weigen
Jiang, Chen
author_facet Lu, Yifei
Guo, Zhongyuan
Zhang, Yujie
Li, Chao
Zhang, Yu
Guo, Qin
Chen, Qinjun
Chen, Xinli
He, Xi
Liu, Lisha
Ruan, Chunhui
Sun, Tao
Ji, Bin
Lu, Weigen
Jiang, Chen
author_sort Lu, Yifei
collection PubMed
description An Alzheimer's disease (AD) brain is featured with the oxidative and inflammatory microenvironment caused by overactivated microglia. In article number 1801586, Chen Jiang and co‐workers design a brain normalizing system to eliminate reactive oxygen species (ROS) and reeducate microglia from an early phase of AD. Through its efficient neuroprotection and microglia modulatory functions, decreased Aβ plaque burdens and improved cognition are achieved. [Image: see text]
format Online
Article
Text
id pubmed-6382302
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-63823022019-03-01 Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019) Lu, Yifei Guo, Zhongyuan Zhang, Yujie Li, Chao Zhang, Yu Guo, Qin Chen, Qinjun Chen, Xinli He, Xi Liu, Lisha Ruan, Chunhui Sun, Tao Ji, Bin Lu, Weigen Jiang, Chen Adv Sci (Weinh) Back Cover An Alzheimer's disease (AD) brain is featured with the oxidative and inflammatory microenvironment caused by overactivated microglia. In article number 1801586, Chen Jiang and co‐workers design a brain normalizing system to eliminate reactive oxygen species (ROS) and reeducate microglia from an early phase of AD. Through its efficient neuroprotection and microglia modulatory functions, decreased Aβ plaque burdens and improved cognition are achieved. [Image: see text] John Wiley and Sons Inc. 2019-02-20 /pmc/articles/PMC6382302/ http://dx.doi.org/10.1002/advs.201970024 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Back Cover
Lu, Yifei
Guo, Zhongyuan
Zhang, Yujie
Li, Chao
Zhang, Yu
Guo, Qin
Chen, Qinjun
Chen, Xinli
He, Xi
Liu, Lisha
Ruan, Chunhui
Sun, Tao
Ji, Bin
Lu, Weigen
Jiang, Chen
Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
title Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
title_full Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
title_fullStr Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
title_full_unstemmed Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
title_short Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
title_sort alzheimer's disease: microenvironment remodeling micelles for alzheimer's disease therapy by early modulation of activated microglia (adv. sci. 4/2019)
topic Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382302/
http://dx.doi.org/10.1002/advs.201970024
work_keys_str_mv AT luyifei alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT guozhongyuan alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT zhangyujie alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT lichao alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT zhangyu alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT guoqin alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT chenqinjun alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT chenxinli alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT hexi alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT liulisha alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT ruanchunhui alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT suntao alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT jibin alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT luweigen alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019
AT jiangchen alzheimersdiseasemicroenvironmentremodelingmicellesforalzheimersdiseasetherapybyearlymodulationofactivatedmicrogliaadvsci42019

Ejemplares similares