Overexpression of thermostable meso-diaminopimelate dehydrogenase to redirect diaminopimelate pathway for increasing L-lysine production in Escherichia coli

Dehydrogenase pathway, one of diaminopimelate pathway, is important to the biosynthesis of L-lysine and peptidoglycan via one single reaction catalyzed by meso-diaminopimelate dehydrogenase (DapDH). In this study, the thermostable DapDH was introduced into diaminopimelate pathway that increased the...

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Detalles Bibliográficos
Autores principales: Xu, Jian-Zhong, Ruan, Hao-Zhe, Liu, Li-Ming, Wang, Lu-Ping, Zhang, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382763/
https://www.ncbi.nlm.nih.gov/pubmed/30787467
http://dx.doi.org/10.1038/s41598-018-37974-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382763/
https://www.ncbi.nlm.nih.gov/pubmed/30787467
http://dx.doi.org/10.1038/s41598-018-37974-w

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