Cargando…
Outcomes of controlled human malaria infection after BCG vaccination
Recent evidence suggests that certain vaccines, including Bacillus-Calmette Guérin (BCG), can induce changes in the innate immune system with non-specific memory characteristics, termed ‘trained immunity’. Here we present the results of a randomised, controlled phase 1 clinical trial in 20 healthy m...
Autores principales: | Walk, Jona, de Bree, L. Charlotte J., Graumans, Wouter, Stoter, Rianne, van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, Teelen, Karina, Hermsen, Cornelus C., Arts, Rob J. W., Behet, Marije C., Keramati, Farid, Moorlag, Simone J. C. F. M., Yang, Annie S. P., van Crevel, Reinout, Aaby, Peter, de Mast, Quirijn, van der Ven, André J. A. M., Stabell Benn, Christine, Netea, Mihai G., Sauerwein, Robert W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382772/ https://www.ncbi.nlm.nih.gov/pubmed/30787276 http://dx.doi.org/10.1038/s41467-019-08659-3 |
Ejemplares similares
-
Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial
por: van der Boor, Saskia C., et al.
Publicado: (2023) -
Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial
por: Walk, Jona, et al.
Publicado: (2017) -
Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial
por: Bijker, Else M., et al.
Publicado: (2014) -
A portfolio of geographically distinct laboratory-adapted Plasmodium falciparum clones with consistent infection rates in Anopheles mosquitoes
por: van de Vegte-Bolmer, Marga, et al.
Publicado: (2021) -
A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model
por: Reuling, Isaie J, et al.
Publicado: (2018)