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The 4717C > G polymorphism in periplakin modulates sensitivity to EGFR inhibitors
The use of EGFR inhibitors on oral squamous cell carcinoma (OSCC) as monotherapy yielded modest clinical outcomes and therefore would benefit from biomarkers that could predict which patient subsets are likely to respond. Here, we determined the efficacy of erlotinib in OSCC cell lines, and by compa...
Autores principales: | Lee, Hui Mei, Kelly, Gregory Michael, Zainal, Nur Syafinaz, Yee, Pei San, Fadlullah, Muhammad Zaki Hidayatullah, Lee, Bernard Kok Bang, Gan, Chai Phei, Patel, Vyomesh, Cheong, Sok Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382785/ https://www.ncbi.nlm.nih.gov/pubmed/30787334 http://dx.doi.org/10.1038/s41598-019-38742-0 |
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