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Genetic programming of macrophages generates an in vitro model for the human erythroid island niche

Red blood cells mature within the erythroblastic island (EI) niche that consists of specialized macrophages surrounded by differentiating erythroblasts. Here we establish an in vitro system to model the human EI niche using macrophages that are derived from human induced pluripotent stem cells (iPSC...

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Detalles Bibliográficos
Autores principales:	Lopez-Yrigoyen, Martha, Yang, Cheng-Tao, Fidanza, Antonella, Cassetta, Luca, Taylor, A. Helen, McCahill, Angela, Sellink, Erica, von Lindern, Marieke, van den Akker, Emile, Mountford, Joanne C., Pollard, Jeffrey W., Forrester, Lesley M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382809/ https://www.ncbi.nlm.nih.gov/pubmed/30787325 http://dx.doi.org/10.1038/s41467-019-08705-0

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