Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes

This study investigated whether irradiation of a specific light wavelength could affect the sex differentiation of fish. We first found that the photoreceptor genes responsible for receiving red, green, and ultraviolet light were expressed in the eyes of medaka during the sex differentiation period....

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Autores principales: Hayasaka, Oki, Takeuchi, Yutaka, Shiozaki, Kazuhiro, Anraku, Kazuhiko, Kotani, Tomonari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382872/
https://www.ncbi.nlm.nih.gov/pubmed/30787482
http://dx.doi.org/10.1038/s41598-019-38908-w
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author Hayasaka, Oki
Takeuchi, Yutaka
Shiozaki, Kazuhiro
Anraku, Kazuhiko
Kotani, Tomonari
author_facet Hayasaka, Oki
Takeuchi, Yutaka
Shiozaki, Kazuhiro
Anraku, Kazuhiko
Kotani, Tomonari
author_sort Hayasaka, Oki
collection PubMed
description This study investigated whether irradiation of a specific light wavelength could affect the sex differentiation of fish. We first found that the photoreceptor genes responsible for receiving red, green, and ultraviolet light were expressed in the eyes of medaka during the sex differentiation period. Second, we revealed that testes developed in 15.9% of genotypic females reared under green light irradiation. These female-to-male sex-reversed fish (i.e. neo-males) showed male-specific secondary sexual characteristics and produced motile sperm. Finally, progeny tests using the sperm of neo-males (XX) and eggs of normal females (XX) revealed that all F1 offspring were female, indicating for the first time in animals that irradiation with light of a specific wavelength can trigger sex reversal.
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spelling pubmed-63828722019-02-25 Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes Hayasaka, Oki Takeuchi, Yutaka Shiozaki, Kazuhiro Anraku, Kazuhiko Kotani, Tomonari Sci Rep Article This study investigated whether irradiation of a specific light wavelength could affect the sex differentiation of fish. We first found that the photoreceptor genes responsible for receiving red, green, and ultraviolet light were expressed in the eyes of medaka during the sex differentiation period. Second, we revealed that testes developed in 15.9% of genotypic females reared under green light irradiation. These female-to-male sex-reversed fish (i.e. neo-males) showed male-specific secondary sexual characteristics and produced motile sperm. Finally, progeny tests using the sperm of neo-males (XX) and eggs of normal females (XX) revealed that all F1 offspring were female, indicating for the first time in animals that irradiation with light of a specific wavelength can trigger sex reversal. Nature Publishing Group UK 2019-02-20 /pmc/articles/PMC6382872/ /pubmed/30787482 http://dx.doi.org/10.1038/s41598-019-38908-w Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hayasaka, Oki
Takeuchi, Yutaka
Shiozaki, Kazuhiro
Anraku, Kazuhiko
Kotani, Tomonari
Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes
title Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes
title_full Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes
title_fullStr Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes
title_full_unstemmed Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes
title_short Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes
title_sort green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka oryzias latipes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382872/
https://www.ncbi.nlm.nih.gov/pubmed/30787482
http://dx.doi.org/10.1038/s41598-019-38908-w
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