Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold

Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to present acyl substrates to a series of enzyme active sites. Many domains from the multimodular PKS that generates the toxin mycolactone disp...

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Detalles Bibliográficos
Autores principales: Moretto, Luisa, Heylen, Rachel, Holroyd, Natalie, Vance, Steven, Broadhurst, R. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382882/
https://www.ncbi.nlm.nih.gov/pubmed/30787330
http://dx.doi.org/10.1038/s41598-019-38747-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382882/
https://www.ncbi.nlm.nih.gov/pubmed/30787330
http://dx.doi.org/10.1038/s41598-019-38747-9

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