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Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold
Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to present acyl substrates to a series of enzyme active sites. Many domains from the multimodular PKS that generates the toxin mycolactone disp...
Autores principales: | Moretto, Luisa, Heylen, Rachel, Holroyd, Natalie, Vance, Steven, Broadhurst, R. William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382882/ https://www.ncbi.nlm.nih.gov/pubmed/30787330 http://dx.doi.org/10.1038/s41598-019-38747-9 |
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