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The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China

OBJECTIVE: The cancer etiology in children and adolescents is largely different with that in adults, and the description in epidemiology still remains deficiency. Therefore, we described the cancer incidence and related epidemiological features in children and adolescents to provide clues for etiolo...

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Autores principales: Chen, Qiong, Guo, Zhen, Liu, Shuzheng, Quan, Peiliang, Cao, Xiaoqin, Guo, Lanwei, Zhang, Shaokai, Sun, Xibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382923/
https://www.ncbi.nlm.nih.gov/pubmed/30659776
http://dx.doi.org/10.1002/cam4.1952
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author Chen, Qiong
Guo, Zhen
Liu, Shuzheng
Quan, Peiliang
Cao, Xiaoqin
Guo, Lanwei
Zhang, Shaokai
Sun, Xibin
author_facet Chen, Qiong
Guo, Zhen
Liu, Shuzheng
Quan, Peiliang
Cao, Xiaoqin
Guo, Lanwei
Zhang, Shaokai
Sun, Xibin
author_sort Chen, Qiong
collection PubMed
description OBJECTIVE: The cancer etiology in children and adolescents is largely different with that in adults, and the description in epidemiology still remains deficiency. Therefore, we described the cancer incidence and related epidemiological features in children and adolescents to provide clues for etiological studies. METHODS: Cancer incidence stratified by age, gender, and areas was calculated using data extracted from population‐based cancer registries in Henan Province, China. All cancer among children aged 0‐19 years were reclassified according to category criteria of the International Classification of Childhood Cancer, 3rd Edition (ICCC‐3). Age‐standardized rate (WSR) was calculated using Segi's world standardized population by the direct method, and it was expressed per million person‐years. RESULTS: The crude cancer incidence and mortality were 87.56 and 36.32 per million person‐years among children aged 0‐19 years, and the WSRs slightly changed compared with crude incidence and mortality, and they were 87.36 and 35.46 per million person‐years. Leukemia and central nervous system neoplasms (CNS) were the most common cancer categories both in children aged 0‐14 years and in adolescents aged 15‐19 years in regardless of gender and areas. Tiny difference of incidence and mortality existed in different age groups across 0‐14 years; however, they were higher in adolescents aged 15‐19 years than that in children aged 0‐14 years. Among children aged 0‐19 years, the cancer incidence and mortality were predominant in boys, and the sex ratio was 1.19; however, it was varied by diagnostic categories. CONCLUSION: This is the first study that described the cancer incidence and mortality among children aged 0‐19 in Henan Province, and it would help researchers to understand the burden and epidemiological characteristics of childhood cancer, and hence suggested clues for the etiological studies.
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spelling pubmed-63829232019-03-01 The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China Chen, Qiong Guo, Zhen Liu, Shuzheng Quan, Peiliang Cao, Xiaoqin Guo, Lanwei Zhang, Shaokai Sun, Xibin Cancer Med Cancer Prevention OBJECTIVE: The cancer etiology in children and adolescents is largely different with that in adults, and the description in epidemiology still remains deficiency. Therefore, we described the cancer incidence and related epidemiological features in children and adolescents to provide clues for etiological studies. METHODS: Cancer incidence stratified by age, gender, and areas was calculated using data extracted from population‐based cancer registries in Henan Province, China. All cancer among children aged 0‐19 years were reclassified according to category criteria of the International Classification of Childhood Cancer, 3rd Edition (ICCC‐3). Age‐standardized rate (WSR) was calculated using Segi's world standardized population by the direct method, and it was expressed per million person‐years. RESULTS: The crude cancer incidence and mortality were 87.56 and 36.32 per million person‐years among children aged 0‐19 years, and the WSRs slightly changed compared with crude incidence and mortality, and they were 87.36 and 35.46 per million person‐years. Leukemia and central nervous system neoplasms (CNS) were the most common cancer categories both in children aged 0‐14 years and in adolescents aged 15‐19 years in regardless of gender and areas. Tiny difference of incidence and mortality existed in different age groups across 0‐14 years; however, they were higher in adolescents aged 15‐19 years than that in children aged 0‐14 years. Among children aged 0‐19 years, the cancer incidence and mortality were predominant in boys, and the sex ratio was 1.19; however, it was varied by diagnostic categories. CONCLUSION: This is the first study that described the cancer incidence and mortality among children aged 0‐19 in Henan Province, and it would help researchers to understand the burden and epidemiological characteristics of childhood cancer, and hence suggested clues for the etiological studies. John Wiley and Sons Inc. 2019-01-18 /pmc/articles/PMC6382923/ /pubmed/30659776 http://dx.doi.org/10.1002/cam4.1952 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Prevention
Chen, Qiong
Guo, Zhen
Liu, Shuzheng
Quan, Peiliang
Cao, Xiaoqin
Guo, Lanwei
Zhang, Shaokai
Sun, Xibin
The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China
title The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China
title_full The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China
title_fullStr The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China
title_full_unstemmed The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China
title_short The cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in Henan Province, China
title_sort cancer incidence and mortality among children and adolescents during the period of 2010‐2014 in henan province, china
topic Cancer Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382923/
https://www.ncbi.nlm.nih.gov/pubmed/30659776
http://dx.doi.org/10.1002/cam4.1952
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