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The 4q25 variant rs13143308T links risk of atrial fibrillation to defective calcium homoeostasis

AIMS: Single nucleotide polymorphisms on chromosome 4q25 have been associated with risk of atrial fibrillation (AF) but the exiguous knowledge of the mechanistic links between these risk variants and underlying electrophysiological alterations hampers their clinical utility. Here, we tested the hypo...

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Detalles Bibliográficos
Autores principales: Herraiz-Martínez, Adela, Llach, Anna, Tarifa, Carmen, Gandía, Jorge, Jiménez-Sabado, Verónica, Lozano-Velasco, Estefanía, Serra, Selma A, Vallmitjana, Alexander, Vázquez Ruiz de Castroviejo, Eduardo, Benítez, Raúl, Aranega, Amelia, Muñoz-Guijosa, Christian, Franco, Diego, Cinca, Juan, Hove-Madsen, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383060/
https://www.ncbi.nlm.nih.gov/pubmed/30219899
http://dx.doi.org/10.1093/cvr/cvy215