Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

mRNA vaccines have the potential to tackle many unmet medical needs that are unable to be addressed with conventional vaccine technologies. A potent and well-tolerated delivery technology is integral to fully realizing the potential of mRNA vaccines. Pre-clinical and clinical studies have demonstrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Hassett, Kimberly J., Benenato, Kerry E., Jacquinet, Eric, Lee, Aisha, Woods, Angela, Yuzhakov, Olga, Himansu, Sunny, Deterling, Jessica, Geilich, Benjamin M., Ketova, Tatiana, Mihai, Cosmin, Lynn, Andy, McFadyen, Iain, Moore, Melissa J., Senn, Joseph J., Stanton, Matthew G., Almarsson, Örn, Ciaramella, Giuseppe, Brito, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383180/
https://www.ncbi.nlm.nih.gov/pubmed/30785039
http://dx.doi.org/10.1016/j.omtn.2019.01.013

Ejemplares similares

Ejemplares similares