Late-onset megaconial myopathy in mice lacking group I Paks

BACKGROUND: Group I Paks are serine/threonine kinases that function as major effectors of the small GTPases Rac1 and Cdc42, and they regulate cytoskeletal dynamics, cell polarity, and transcription. We previously demonstrated that Pak1 and Pak2 function redundantly to promote skeletal myoblast diffe...

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Detalles Bibliográficos
Autores principales: Joseph, Giselle A., Hung, Margaret, Goel, Aviva J., Hong, Mingi, Rieder, Marysia-Kolbe, Beckmann, Noam D., Serasinghe, Madhavika N., Chipuk, Jerry E., Devarakonda, Parvathi M., Goldhamer, David J., Aldana-Hernandez, Paulina, Curtis, Jonathan, Jacobs, René L., Krauss, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383276/
https://www.ncbi.nlm.nih.gov/pubmed/30791960
http://dx.doi.org/10.1186/s13395-019-0191-4

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