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Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors

A paper published in BMC Biology characterises biophysically oligomeric and filamentous structures formed spontaneously by the Toll-like receptor signalling adaptor MyD88. Naturally occurring mutants of MyD88 that cause immunodeficiency are unable to form these structures. By contrast a somatic muta...

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Detalles Bibliográficos
Autor principal:	Gay, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383289/ https://www.ncbi.nlm.nih.gov/pubmed/30786893 http://dx.doi.org/10.1186/s12915-019-0637-5

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