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Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children

The objective of this study was to evaluate the association between salivary 1,5-anhydroglucitol (AG), vitamins A (VA), C (VC), and E (VE), and caries risk in children. 100 healthy children aged between 6 and 13 years were divided into two equal groups of caries-free (DMFS/dmfs=0) and caries active...

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Autores principales: Syed, Sadatullah, Yassin, Syed M., Dawasaz, Ali A., Amanullah, Mohammed, Alshahrani, Ibrahim, Togoo, Rafi Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383396/
https://www.ncbi.nlm.nih.gov/pubmed/30881987
http://dx.doi.org/10.1155/2019/4503450
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author Syed, Sadatullah
Yassin, Syed M.
Dawasaz, Ali A.
Amanullah, Mohammed
Alshahrani, Ibrahim
Togoo, Rafi Ahmad
author_facet Syed, Sadatullah
Yassin, Syed M.
Dawasaz, Ali A.
Amanullah, Mohammed
Alshahrani, Ibrahim
Togoo, Rafi Ahmad
author_sort Syed, Sadatullah
collection PubMed
description The objective of this study was to evaluate the association between salivary 1,5-anhydroglucitol (AG), vitamins A (VA), C (VC), and E (VE), and caries risk in children. 100 healthy children aged between 6 and 13 years were divided into two equal groups of caries-free (DMFS/dmfs=0) and caries active (DMFS/dmfs>3). Unstimulated midmorning saliva was collected from all the children and the levels of salivary AG and vitamins A, C, and E were measured. Caries risk assessment was done using American Academy of Pediatric Dentistry Caries Assessment Tool. Analysis of salivary AG and vitamins was performed using a commercially available ELISA kit. Low levels of AG were present in caries active and high caries risk groups compared to caries-free and low/medium caries risk groups. This difference is statistically significant (p < 0.05). A strong negative correlation between AG and caries activity was observed in the caries active group. VA was not related to caries activity, while VC and VE displayed a statistically significant correlation (p < 0.05). Similarly, a strong negative correlation was observed between the levels of AG and high caries risk group. Salivary AG, VC, and VE together are related to caries risk in caries active children. These salivary parameters can act as indicator of caries status in children.
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spelling pubmed-63833962019-03-17 Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children Syed, Sadatullah Yassin, Syed M. Dawasaz, Ali A. Amanullah, Mohammed Alshahrani, Ibrahim Togoo, Rafi Ahmad Biomed Res Int Research Article The objective of this study was to evaluate the association between salivary 1,5-anhydroglucitol (AG), vitamins A (VA), C (VC), and E (VE), and caries risk in children. 100 healthy children aged between 6 and 13 years were divided into two equal groups of caries-free (DMFS/dmfs=0) and caries active (DMFS/dmfs>3). Unstimulated midmorning saliva was collected from all the children and the levels of salivary AG and vitamins A, C, and E were measured. Caries risk assessment was done using American Academy of Pediatric Dentistry Caries Assessment Tool. Analysis of salivary AG and vitamins was performed using a commercially available ELISA kit. Low levels of AG were present in caries active and high caries risk groups compared to caries-free and low/medium caries risk groups. This difference is statistically significant (p < 0.05). A strong negative correlation between AG and caries activity was observed in the caries active group. VA was not related to caries activity, while VC and VE displayed a statistically significant correlation (p < 0.05). Similarly, a strong negative correlation was observed between the levels of AG and high caries risk group. Salivary AG, VC, and VE together are related to caries risk in caries active children. These salivary parameters can act as indicator of caries status in children. Hindawi 2019-02-07 /pmc/articles/PMC6383396/ /pubmed/30881987 http://dx.doi.org/10.1155/2019/4503450 Text en Copyright © 2019 Sadatullah Syed et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Syed, Sadatullah
Yassin, Syed M.
Dawasaz, Ali A.
Amanullah, Mohammed
Alshahrani, Ibrahim
Togoo, Rafi Ahmad
Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children
title Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children
title_full Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children
title_fullStr Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children
title_full_unstemmed Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children
title_short Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children
title_sort salivary 1,5-anhydroglucitol and vitamin levels in relation to caries risk in children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383396/
https://www.ncbi.nlm.nih.gov/pubmed/30881987
http://dx.doi.org/10.1155/2019/4503450
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