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Adaptations in Protein Expression and Regulated Activity of Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure

Pyruvate dehydrogenase (PDH) complex, a multienzyme complex at the nexus of glycolytic and Krebs cycles, provides acetyl-CoA to the Krebs cycle and NADH to complex I thus supporting a critical role in mitochondrial energy production and cellular survival. PDH activity is regulated by pyruvate dehydr...

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Detalles Bibliográficos
Autores principales:	Sheeran, Freya L., Angerosa, Julie, Liaw, Norman Y., Cheung, Michael M., Pepe, Salvatore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383428/ https://www.ncbi.nlm.nih.gov/pubmed/30881593 http://dx.doi.org/10.1155/2019/4532592

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