Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection

Xylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty...

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Autores principales: Rajapaksha, Suranga M., Gerken, Katherine, Archer, Todd, Lathan, Patty, Liyanage, Achala S., Mlsna, Deb, Mlsna, Todd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383431/
https://www.ncbi.nlm.nih.gov/pubmed/30881724
http://dx.doi.org/10.1155/2019/1690153
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author Rajapaksha, Suranga M.
Gerken, Katherine
Archer, Todd
Lathan, Patty
Liyanage, Achala S.
Mlsna, Deb
Mlsna, Todd E.
author_facet Rajapaksha, Suranga M.
Gerken, Katherine
Archer, Todd
Lathan, Patty
Liyanage, Achala S.
Mlsna, Deb
Mlsna, Todd E.
author_sort Rajapaksha, Suranga M.
collection PubMed
description Xylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty if these chewing gums are still dangerous to dogs after they have been partially consumed. In this work, a reliable low-cost analytical method has been developed to quantify the xylitol in sugar-free gum samples. Xylitol was extracted from gum samples using water as a solvent. Extractions were analyzed by GC-MS with direct aqueous injection (DAI). This method was successfully applied to over 120 samples including fresh gum and 5 min, 15 min, and 30 min chewed gum samples.
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spelling pubmed-63834312019-03-17 Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection Rajapaksha, Suranga M. Gerken, Katherine Archer, Todd Lathan, Patty Liyanage, Achala S. Mlsna, Deb Mlsna, Todd E. J Anal Methods Chem Research Article Xylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty if these chewing gums are still dangerous to dogs after they have been partially consumed. In this work, a reliable low-cost analytical method has been developed to quantify the xylitol in sugar-free gum samples. Xylitol was extracted from gum samples using water as a solvent. Extractions were analyzed by GC-MS with direct aqueous injection (DAI). This method was successfully applied to over 120 samples including fresh gum and 5 min, 15 min, and 30 min chewed gum samples. Hindawi 2019-02-07 /pmc/articles/PMC6383431/ /pubmed/30881724 http://dx.doi.org/10.1155/2019/1690153 Text en Copyright © 2019 Suranga M. Rajapaksha et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rajapaksha, Suranga M.
Gerken, Katherine
Archer, Todd
Lathan, Patty
Liyanage, Achala S.
Mlsna, Deb
Mlsna, Todd E.
Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
title Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
title_full Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
title_fullStr Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
title_full_unstemmed Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
title_short Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
title_sort extraction and analysis of xylitol in sugar-free gum samples by gc-ms with direct aqueous injection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383431/
https://www.ncbi.nlm.nih.gov/pubmed/30881724
http://dx.doi.org/10.1155/2019/1690153
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