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Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis

BACKGROUND: PGC-1α can be activated by deacetylation reactions catalyzed by SIRT1. Resveratrol is currently known as a potent activator of SIRT1. However, it is unknown whether the renal-protective effect of resveratrol is further related to activation of the podocyte SIRT1/PGC-1α pathway. MATERIAL/...

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Detalles Bibliográficos
Autores principales:	Zhang, Tao, Chi, Yanqing, Ren, Yunzhuo, Du, Chunyang, Shi, Yonghong, Li, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383436/ https://www.ncbi.nlm.nih.gov/pubmed/30765684 http://dx.doi.org/10.12659/MSM.911714

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