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Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment

Nanotechnology has been extensively utilized in the design and development of powerful strategies for drug delivery and cancer theranostic. Nanoplatforms as a drug delivery system have many advantages such as in vivo imaging, combined drug delivery, extended circulation time, and systemic controlled...

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Detalles Bibliográficos
Autores principales: Li, Lei, Wang, Junqing, Kong, Hangru, Zeng, Yun, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383616/
https://www.ncbi.nlm.nih.gov/pubmed/30815042
http://dx.doi.org/10.1080/14686996.2018.1528850
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author Li, Lei
Wang, Junqing
Kong, Hangru
Zeng, Yun
Liu, Gang
author_facet Li, Lei
Wang, Junqing
Kong, Hangru
Zeng, Yun
Liu, Gang
author_sort Li, Lei
collection PubMed
description Nanotechnology has been extensively utilized in the design and development of powerful strategies for drug delivery and cancer theranostic. Nanoplatforms as a drug delivery system have many advantages such as in vivo imaging, combined drug delivery, extended circulation time, and systemic controlled release. The functional biomimetic drug delivery could be realized by incorporating stimuli-responsive (pH, temperature, redox potential, etc.) properties into the nanocarrier system, allowing them to bypass biological barriers and arrive at the targeted area. In this review, we discuss the role of internal stimuli-responsive nanocarrier system for imaging and drug delivery in cancer therapy. The development of internal stimuli-responsive nanoparticles is highlighted for precision drug delivery applications, with a particular focus on in vivo imaging, drug release performance, and therapeutic benefits.
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spelling pubmed-63836162019-02-27 Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment Li, Lei Wang, Junqing Kong, Hangru Zeng, Yun Liu, Gang Sci Technol Adv Mater Focus on Bio-inspired nanomaterials Nanotechnology has been extensively utilized in the design and development of powerful strategies for drug delivery and cancer theranostic. Nanoplatforms as a drug delivery system have many advantages such as in vivo imaging, combined drug delivery, extended circulation time, and systemic controlled release. The functional biomimetic drug delivery could be realized by incorporating stimuli-responsive (pH, temperature, redox potential, etc.) properties into the nanocarrier system, allowing them to bypass biological barriers and arrive at the targeted area. In this review, we discuss the role of internal stimuli-responsive nanocarrier system for imaging and drug delivery in cancer therapy. The development of internal stimuli-responsive nanoparticles is highlighted for precision drug delivery applications, with a particular focus on in vivo imaging, drug release performance, and therapeutic benefits. Taylor & Francis 2018-10-26 /pmc/articles/PMC6383616/ /pubmed/30815042 http://dx.doi.org/10.1080/14686996.2018.1528850 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Focus on Bio-inspired nanomaterials
Li, Lei
Wang, Junqing
Kong, Hangru
Zeng, Yun
Liu, Gang
Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
title Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
title_full Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
title_fullStr Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
title_full_unstemmed Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
title_short Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
title_sort functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment
topic Focus on Bio-inspired nanomaterials
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383616/
https://www.ncbi.nlm.nih.gov/pubmed/30815042
http://dx.doi.org/10.1080/14686996.2018.1528850
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