Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)

Neuroimaging in the context of examining atypical parkinsonian tauopathies is an evolving matter. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) bring tools, which may be reasonable in supplementary examination, however cannot be interpreted as a gold stand...

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Autores principales: Alster, Piotr, Madetko, Natalia Katarzyna, Koziorowski, Dariusz Mariusz, Królicki, Leszek, Budrewicz, Sławomir, Friedman, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383629/
https://www.ncbi.nlm.nih.gov/pubmed/30837933
http://dx.doi.org/10.3389/fneur.2019.00101
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author Alster, Piotr
Madetko, Natalia Katarzyna
Koziorowski, Dariusz Mariusz
Królicki, Leszek
Budrewicz, Sławomir
Friedman, Andrzej
author_facet Alster, Piotr
Madetko, Natalia Katarzyna
Koziorowski, Dariusz Mariusz
Królicki, Leszek
Budrewicz, Sławomir
Friedman, Andrzej
author_sort Alster, Piotr
collection PubMed
description Neuroimaging in the context of examining atypical parkinsonian tauopathies is an evolving matter. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) bring tools, which may be reasonable in supplementary examination, however cannot be interpreted as a gold standard for correct diagnosis. The review presents advantages and limitations of tau radiotracers in PET, metabolic PET and perfusion SPECT. The aim of this paper is to highlight the possibilities and boundaries in the supplementary examination of tauopathic parkinsonian syndromes.
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spelling pubmed-63836292019-03-05 Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS) Alster, Piotr Madetko, Natalia Katarzyna Koziorowski, Dariusz Mariusz Królicki, Leszek Budrewicz, Sławomir Friedman, Andrzej Front Neurol Neurology Neuroimaging in the context of examining atypical parkinsonian tauopathies is an evolving matter. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) bring tools, which may be reasonable in supplementary examination, however cannot be interpreted as a gold standard for correct diagnosis. The review presents advantages and limitations of tau radiotracers in PET, metabolic PET and perfusion SPECT. The aim of this paper is to highlight the possibilities and boundaries in the supplementary examination of tauopathic parkinsonian syndromes. Frontiers Media S.A. 2019-02-14 /pmc/articles/PMC6383629/ /pubmed/30837933 http://dx.doi.org/10.3389/fneur.2019.00101 Text en Copyright © 2019 Alster, Madetko, Koziorowski, Królicki, Budrewicz and Friedman. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Alster, Piotr
Madetko, Natalia Katarzyna
Koziorowski, Dariusz Mariusz
Królicki, Leszek
Budrewicz, Sławomir
Friedman, Andrzej
Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)
title Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)
title_full Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)
title_fullStr Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)
title_full_unstemmed Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)
title_short Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)
title_sort accumulation of tau protein, metabolism and perfusion—application and efficacy of positron emission tomography (pet) and single photon emission computed tomography (spect) imaging in the examination of progressive supranuclear palsy (psp) and corticobasal syndrome (cbs)
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383629/
https://www.ncbi.nlm.nih.gov/pubmed/30837933
http://dx.doi.org/10.3389/fneur.2019.00101
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