Tumor cells containing the African-Centric S47 variant of TP53 show increased Warburg metabolism

Mutations in the TP53 tumor suppressor gene remain a hallmark of human cancer. In addition to mutation of TP53, single nucleotide polymorphisms (SNPs) in this gene can have a profound impact on p53 function, and can affect cancer risk as well as other p53 functions. Wild type (WT) p53 contains a pro...

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Detalles Bibliográficos
Autores principales: Barnoud, Thibaut, Parris, Joshua L.D., Murphy, Maureen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383823/
https://www.ncbi.nlm.nih.gov/pubmed/30838093
http://dx.doi.org/10.18632/oncotarget.26660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383823/
https://www.ncbi.nlm.nih.gov/pubmed/30838093
http://dx.doi.org/10.18632/oncotarget.26660

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