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Tumor cells containing the African-Centric S47 variant of TP53 show increased Warburg metabolism
Mutations in the TP53 tumor suppressor gene remain a hallmark of human cancer. In addition to mutation of TP53, single nucleotide polymorphisms (SNPs) in this gene can have a profound impact on p53 function, and can affect cancer risk as well as other p53 functions. Wild type (WT) p53 contains a pro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383823/ https://www.ncbi.nlm.nih.gov/pubmed/30838093 http://dx.doi.org/10.18632/oncotarget.26660 |