The PHO signaling pathway directs lipid remodeling in Cryptococcus neoformans via DGTS synthase to recycle phosphate during phosphate deficiency

The phosphate sensing and acquisition (PHO) pathway of Cryptococcus neoformans is essential for growth in phosphate-limiting conditions and for dissemination of infection in a mouse model. Its key transcription factor, Pho4, regulates expression of genes controlling the acquisition of phosphate from...

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Detalles Bibliográficos
Autores principales: Lev, Sophie, Rupasinghe, Thusitha, Desmarini, Desmarini, Kaufman-Francis, Keren, Sorrell, Tania Christine, Roessner, Ute, Djordjevic, Julianne Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383925/
https://www.ncbi.nlm.nih.gov/pubmed/30789965
http://dx.doi.org/10.1371/journal.pone.0212651

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