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Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Microglia are resident immune cells that play critical roles in maintaining the normal physiology of the central nervous system (CNS). Remarkably, microglia have an intrinsic capacity to repopulate themselves after acute ablation. However, the underlying mechanisms that drive such restoration remain...

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Detalles Bibliográficos
Autores principales: Zhan, Lihong, Krabbe, Grietje, Du, Fei, Jones, Ian, Reichert, Meredith C., Telpoukhovskaia, Maria, Kodama, Lay, Wang, Chao, Cho, Seo-hyun, Sayed, Faten, Li, Yaqiao, Le, David, Zhou, Yungui, Shen, Yin, West, Brian, Gan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383943/
https://www.ncbi.nlm.nih.gov/pubmed/30735499
http://dx.doi.org/10.1371/journal.pbio.3000134