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Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
Microglia are resident immune cells that play critical roles in maintaining the normal physiology of the central nervous system (CNS). Remarkably, microglia have an intrinsic capacity to repopulate themselves after acute ablation. However, the underlying mechanisms that drive such restoration remain...
Autores principales: | Zhan, Lihong, Krabbe, Grietje, Du, Fei, Jones, Ian, Reichert, Meredith C., Telpoukhovskaia, Maria, Kodama, Lay, Wang, Chao, Cho, Seo-hyun, Sayed, Faten, Li, Yaqiao, Le, David, Zhou, Yungui, Shen, Yin, West, Brian, Gan, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383943/ https://www.ncbi.nlm.nih.gov/pubmed/30735499 http://dx.doi.org/10.1371/journal.pbio.3000134 |
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