A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6

Endotoxin, a component of the outer membrane of Gram-negative bacteria, has been extensively studied as a stimulator of the innate immune response. However, the temporal aspects and exposure-response relationship of endotoxin and resulting cytokine induction and tolerance development is less well de...

Descripción completa

Detalles Bibliográficos
Autores principales: Thorsted, Anders, Bouchene, Salim, Tano, Eva, Castegren, Markus, Lipcsey, Miklós, Sjölin, Jan, Karlsson, Mats O., Friberg, Lena E., Nielsen, Elisabet I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383944/
https://www.ncbi.nlm.nih.gov/pubmed/30789941
http://dx.doi.org/10.1371/journal.pone.0211981

Ejemplares similares

Ejemplares similares