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Adaptive downregulation of Cl(-)/HCO(3)(-) exchange activity in rat hepatocytes under experimental obstructive cholestasis

In obstructive cholestasis, there is an integral adaptive response aimed to diminish the bile flow and minimize the injury of bile ducts caused by increased intraluminal pressure and harmful levels of bile salts and bilirrubin. Canalicular bicarbonate secretion, driven by the anion exchanger 2 (AE2)...

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Detalles Bibliográficos
Autores principales:	Miszczuk, Gisel S., Banales, Jesus M., Zucchetti, Andrés E., Pisani, Gerardo B., Boaglio, Andrea C., Saez, Elena, Medina, Juan F., Roma, Marcelo G., Crocenzi, Fernando A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383990/ https://www.ncbi.nlm.nih.gov/pubmed/30789925 http://dx.doi.org/10.1371/journal.pone.0212215

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