Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway

Glutamate toxicity-mediated mitochondrial dysfunction and neuronal cell death are involved in the pathogenesis of several neurodegenerative diseases as well as acute brain ischemia/stroke. In this study, we investigated the neuroprotective mechanism of dieckol (DEK), one of the phlorotannins isolate...

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Detalles Bibliográficos
Autores principales: Cui, Yanji, Amarsanaa, Khulan, Lee, Ji Hyung, Rhim, Jong-Kook, Kwon, Jung Mi, Kim, Seong-Ho, Park, Joo Min, Jung, Sung-Cherl, Eun, Su-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384196/
https://www.ncbi.nlm.nih.gov/pubmed/30820156
http://dx.doi.org/10.4196/kjpp.2019.23.2.121

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