Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine

Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in the US and Europe is hindered by reactogenicity in previously exposed individuals. The aim of this study was to id...

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Detalles Bibliográficos
Autores principales: Scholzen, Anja, Richard, Guilhem, Moise, Leonard, Baeten, Laurie A., Reeves, Patrick M., Martin, William D., Brauns, Timothy A., Boyle, Christine M., Raju Paul, Susan, Bucala, Richard, Bowen, Richard A., Garritsen, Anja, De Groot, Anne S., Sluder, Ann E., Poznansky, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384241/
https://www.ncbi.nlm.nih.gov/pubmed/30828331
http://dx.doi.org/10.3389/fimmu.2019.00207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384241/
https://www.ncbi.nlm.nih.gov/pubmed/30828331
http://dx.doi.org/10.3389/fimmu.2019.00207

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