Cargando…

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract

Mucociliary clearance (MCC), considered as a collaboration of mucus secreted from goblet cells, the airway surface liquid layer, and the beating of cilia of ciliated cells, is the airways’ defense system against airborne contaminants. Because the process is well described at the molecular level, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yepiskoposyan, Hasmik, Talikka, Marja, Vavassori, Stefano, Martin, Florian, Sewer, Alain, Gubian, Sylvain, Luettich, Karsta, Peitsch, Manuel Claude, Hoeng, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384416/ https://www.ncbi.nlm.nih.gov/pubmed/30828347 http://dx.doi.org/10.3389/fgene.2019.00087

Ejemplares similares

An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure
por: Luettich, Karsta, et al.
Publicado: (2021)

Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium
por: Talikka, Marja, et al.
Publicado: (2017)

Systems biology approach highlights mechanistic differences between Crohn’s disease and ulcerative colitis
por: Ruiz Castro, Pedro A., et al.
Publicado: (2021)

Causal Biological Network Model for Inflammasome Signaling Applied for Interpreting Transcriptomic Changes in Various Inflammatory States
por: Yepiskoposyan, Hasmik, et al.
Publicado: (2022)

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model
por: Luettich, Karsta, et al.
Publicado: (2014)

NPA: an R package for computing network perturbation amplitudes using gene expression data and two-layer networks
por: Martin, Florian, et al.
Publicado: (2019)

Erratum: Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract
Publicado: (2020)

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models
por: Martin, Florian, et al.
Publicado: (2014)

Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression
por: Sewer, Alain, et al.
Publicado: (2014)

Systems Toxicology Approach for Assessing Developmental Neurotoxicity in Larval Zebrafish
por: Li, Roman A., et al.
Publicado: (2021)

Causal biological network models for reactive astrogliosis: a systems approach to neuroinflammation
por: Barkhuizen, Melinda, et al.
Publicado: (2022)

Effects of cigarette smoke exposure on a mouse model of multiple sclerosis
por: Ho, Jenny, et al.
Publicado: (2022)

Effects of airborne pollutants on mucociliary clearance.
por: Wolff, R K
Publicado: (1986)

Aging Diminishes Mucociliary Clearance of the Lung
por: Bailey, Kristina L.
Publicado: (2022)

Semi-Automated Curation Allows Causal Network Model Building for the Quantification of Age-Dependent Plaque Progression in ApoE(−/−) Mouse
por: Szostak, Justyna, et al.
Publicado: (2016)

Confero: an integrated contrast data and gene set platform for computational analysis and biological interpretation of omics data
por: Hermida, Leandro, et al.
Publicado: (2013)

Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems
por: Boué, Stéphanie, et al.
Publicado: (2015)

Hookah smoking impairs nasal mucociliary clearance
por: Arıcıgil, Mitat, et al.
Publicado: (2018)

Editorial: Mucus and the mucociliary interface: continuity and clearance
por: Hill, David B.
Publicado: (2023)

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice
por: Titz, Bjoern, et al.
Publicado: (2020)

Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
por: Titz, Bjoern, et al.
Publicado: (2016)

Physiological and biological characterization of smokers with and without COPD
por: Chaudhary, Nveed, et al.
Publicado: (2018)

A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2)
por: Martin, Florian, et al.
Publicado: (2019)

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures
por: Schlage, Walter K., et al.
Publicado: (2014)

Tobacco Alkaloid Assessment in a DSS-Induced Colitis Mouse Model with a Fully Humanized Immune System
por: Verhaeghe, Catherine, et al.
Publicado: (2023)

Construction of biological networks from unstructured information based on a semi-automated curation workflow
por: Szostak, Justyna, et al.
Publicado: (2015)

The effects on mucociliary clearance of prednisone associated with bronchial section
por: de Oliveira Braga, Karina Andrighetti, et al.
Publicado: (2012)

Mathematical Modeling of Mucociliary Clearance: A Mini-Review
por: Xu, Ling, et al.
Publicado: (2019)

The Effects of the Anti-aging Protein Klotho on Mucociliary Clearance
por: Garth, Jaleesa, et al.
Publicado: (2020)

Differential effect of anesthetics on mucociliary clearance in vivo in mice
por: Feldman, Kyle S., et al.
Publicado: (2021)

Characterizing Mucociliary Clearance in Young Children with Cystic Fibrosis
por: Laube, Beth L., et al.
Publicado: (2022)

Nasal Mucociliary Clearance in Smokers: A Systematic Review
por: Prasetyo, Awal, et al.
Publicado: (2021)

Airway Epithelial Nucleotide Release Contributes to Mucociliary Clearance
por: van Heusden, Catharina, et al.
Publicado: (2021)

Regional Differences in Mucociliary Clearance in the Upper and Lower Airways
por: Rogers, Troy D., et al.
Publicado: (2022)

Tromethamine improves mucociliary clearance in cystic fibrosis pigs
por: Ash, Jamison J., et al.
Publicado: (2022)

Comparison of the basic morphology and function of 3D lung epithelial cultures derived from several donors
por: Bovard, David, et al.
Publicado: (2020)

A mechanism of airway injury in an epithelial model of mucociliary clearance
por: O'Brien, Darryl W, et al.
Publicado: (2004)

Effects of second hand smoke on airway secretion and mucociliary clearance
por: Liu, Yanyan, et al.
Publicado: (2012)

Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists
por: Brant, Tereza C S, et al.
Publicado: (2014)

A quantitative interspecies comparison of the respiratory mucociliary clearance mechanism
por: Burn, Andreas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0snfp8mbpicn1rpm7dqrv93pab