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The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction
INTRODUCTION: The aim of this study was to analyze whether periodontal treatment affects the cardiovascular risk profile of patients after myocardial infarction (MI). MATERIAL AND METHODS: The study included 30 patients with chronic periodontitis (ChP). Sociodemographic and medical variables were co...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Polish Society of Experimental and Clinical Immunology
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384430/ https://www.ncbi.nlm.nih.gov/pubmed/30799993 http://dx.doi.org/10.5114/ceji.2018.81356 |
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author | Górski, Bartłomiej Górska, Renata |
author_facet | Górski, Bartłomiej Górska, Renata |
author_sort | Górski, Bartłomiej |
collection | PubMed |
description | INTRODUCTION: The aim of this study was to analyze whether periodontal treatment affects the cardiovascular risk profile of patients after myocardial infarction (MI). MATERIAL AND METHODS: The study included 30 patients with chronic periodontitis (ChP). Sociodemographic and medical variables were collected. Patients were provided with scaling and root planing (SRP) 3 months after MI (1(st) visit). Periodontal examination and blood tests were performed immediately before SRP, then 1 month and 6 months after treatment (2(nd) and 3(rd) visit, respectively). RESULTS: A statistically significant decrease in blood hsCRP concentration and a decrease in the number of white blood cells (WBC) and neutrophils between the first and the second visit were observed. At 6 months after SRP, the mean platelet volume (MPV) had increased with respect to the value at 1 month after treatment. Multivariate analysis showed that the associations between: 1) change in LDL-C concentration and change in approximal plaque index value (b = –0.546, p = 0.005); 2) change in the number of monocytes and change in the plaque index value (b = 0.616, p = 0.01); 3) change in MPV and change in probing pocket depth (b = 0.567, p = 0.018) are all independent of the classic cardiovascular risk factors. CONCLUSIONS: The obtained results indicate the existence of a relationship between the state of periodontal tissues on one hand and mediators of atherosclerosis and the number of immunologically competent cells on the other hand. |
format | Online Article Text |
id | pubmed-6384430 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Polish Society of Experimental and Clinical Immunology |
record_format | MEDLINE/PubMed |
spelling | pubmed-63844302019-02-22 The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction Górski, Bartłomiej Górska, Renata Cent Eur J Immunol Clinical Immunology INTRODUCTION: The aim of this study was to analyze whether periodontal treatment affects the cardiovascular risk profile of patients after myocardial infarction (MI). MATERIAL AND METHODS: The study included 30 patients with chronic periodontitis (ChP). Sociodemographic and medical variables were collected. Patients were provided with scaling and root planing (SRP) 3 months after MI (1(st) visit). Periodontal examination and blood tests were performed immediately before SRP, then 1 month and 6 months after treatment (2(nd) and 3(rd) visit, respectively). RESULTS: A statistically significant decrease in blood hsCRP concentration and a decrease in the number of white blood cells (WBC) and neutrophils between the first and the second visit were observed. At 6 months after SRP, the mean platelet volume (MPV) had increased with respect to the value at 1 month after treatment. Multivariate analysis showed that the associations between: 1) change in LDL-C concentration and change in approximal plaque index value (b = –0.546, p = 0.005); 2) change in the number of monocytes and change in the plaque index value (b = 0.616, p = 0.01); 3) change in MPV and change in probing pocket depth (b = 0.567, p = 0.018) are all independent of the classic cardiovascular risk factors. CONCLUSIONS: The obtained results indicate the existence of a relationship between the state of periodontal tissues on one hand and mediators of atherosclerosis and the number of immunologically competent cells on the other hand. Polish Society of Experimental and Clinical Immunology 2018-12-31 2018 /pmc/articles/PMC6384430/ /pubmed/30799993 http://dx.doi.org/10.5114/ceji.2018.81356 Text en Copyright: © 2018 Polish Society of Experimental and Clinical Immunology http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Clinical Immunology Górski, Bartłomiej Górska, Renata The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
title | The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
title_full | The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
title_fullStr | The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
title_full_unstemmed | The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
title_short | The impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
title_sort | impact of periodontal treatment on inflammatory markers and cellular parameters associated with atherosclerosis in patients after myocardial infarction |
topic | Clinical Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384430/ https://www.ncbi.nlm.nih.gov/pubmed/30799993 http://dx.doi.org/10.5114/ceji.2018.81356 |
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