Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects

New quinazolinone derivatives of the marine-derived alkaloids fiscalin B (3) and fumiquinazoline G (1), with neuroprotective and antitumor effects, were synthesized. Eleven quinazolinone-containing indole alkaloids were synthesized, proceeding the anti analogs via a one-pot method, and the syn analo...

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Detalles Bibliográficos
Autores principales: Long, Solida, Resende, Diana I. S. P., Kijjoa, Anake, Silva, Artur M. S., Fernandes, Ricardo, Xavier, Cristina P. R., Vasconcelos, M. Helena, Sousa, Emília, Pinto, Madalena M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384550/
https://www.ncbi.nlm.nih.gov/pubmed/30717179
http://dx.doi.org/10.3390/molecules24030534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384550/
https://www.ncbi.nlm.nih.gov/pubmed/30717179
http://dx.doi.org/10.3390/molecules24030534

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