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Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)

The distribution of pyrethroid insecticide deltamethrin (DLM) in goat milk and cheese (caciotta) following pour-on administration at the sheep dosage (DLMS-10 mL/60 kg body weight) and double dosage (DLMD-20 mL/60 kg body weight) was studied. DLM concentrations were measured in milk collected from s...

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Autores principales: Marrone, Raffaele, Ramkumar, Abilasha, Smaldone, Giorgio, Rufrano, Domenico, Chirollo, Claudia, Veneziano, Vincenzo, Danaher, Martin, Anastasio, Aniello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384561/
https://www.ncbi.nlm.nih.gov/pubmed/30709021
http://dx.doi.org/10.3390/molecules24030517
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author Marrone, Raffaele
Ramkumar, Abilasha
Smaldone, Giorgio
Rufrano, Domenico
Chirollo, Claudia
Veneziano, Vincenzo
Danaher, Martin
Anastasio, Aniello
author_facet Marrone, Raffaele
Ramkumar, Abilasha
Smaldone, Giorgio
Rufrano, Domenico
Chirollo, Claudia
Veneziano, Vincenzo
Danaher, Martin
Anastasio, Aniello
author_sort Marrone, Raffaele
collection PubMed
description The distribution of pyrethroid insecticide deltamethrin (DLM) in goat milk and cheese (caciotta) following pour-on administration at the sheep dosage (DLMS-10 mL/60 kg body weight) and double dosage (DLMD-20 mL/60 kg body weight) was studied. DLM concentrations were measured in milk collected from study animals (No.14) before treatment and at 2, 4, 8, 12, 16, 24, 30, 36, 48, 56, until 168 h (7 days) post treatment and in caciotta cheese at 12 and 24 h post treatment. At both dosages, the maximum level of DLM residues in goat milk and cheese was below the maximum residue limit (MRL) of 20 μg kg(−1) established for bovine milk (EU No 37/2010) at all time points. However, in terms of public health, higher DLM residues in cheese show that further specific studies should be performed on double dosage efficacy and pharmacokinetic and pharmacodynamics properties of ectoparasites in lactating goats.
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spelling pubmed-63845612019-02-23 Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus) Marrone, Raffaele Ramkumar, Abilasha Smaldone, Giorgio Rufrano, Domenico Chirollo, Claudia Veneziano, Vincenzo Danaher, Martin Anastasio, Aniello Molecules Article The distribution of pyrethroid insecticide deltamethrin (DLM) in goat milk and cheese (caciotta) following pour-on administration at the sheep dosage (DLMS-10 mL/60 kg body weight) and double dosage (DLMD-20 mL/60 kg body weight) was studied. DLM concentrations were measured in milk collected from study animals (No.14) before treatment and at 2, 4, 8, 12, 16, 24, 30, 36, 48, 56, until 168 h (7 days) post treatment and in caciotta cheese at 12 and 24 h post treatment. At both dosages, the maximum level of DLM residues in goat milk and cheese was below the maximum residue limit (MRL) of 20 μg kg(−1) established for bovine milk (EU No 37/2010) at all time points. However, in terms of public health, higher DLM residues in cheese show that further specific studies should be performed on double dosage efficacy and pharmacokinetic and pharmacodynamics properties of ectoparasites in lactating goats. MDPI 2019-01-31 /pmc/articles/PMC6384561/ /pubmed/30709021 http://dx.doi.org/10.3390/molecules24030517 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Marrone, Raffaele
Ramkumar, Abilasha
Smaldone, Giorgio
Rufrano, Domenico
Chirollo, Claudia
Veneziano, Vincenzo
Danaher, Martin
Anastasio, Aniello
Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)
title Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)
title_full Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)
title_fullStr Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)
title_full_unstemmed Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)
title_short Deltamethrin Residues in Milk and Cheese of Lactating Goats (Capra hircus)
title_sort deltamethrin residues in milk and cheese of lactating goats (capra hircus)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384561/
https://www.ncbi.nlm.nih.gov/pubmed/30709021
http://dx.doi.org/10.3390/molecules24030517
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