Cargando…

Exploratory Cortex Metabolic Profiling Revealed the Sedative Effect of Amber in Pentylenetetrazole-Induced Epilepsy-Like Mice

Epilepsy is a common clinical syndrome characterized by sudden and recurrent attacks and temporary central nervous system dysfunction caused by excessive discharge of neurons in the brain. Amber, a fossilized organic substance formed by the resins of conifers and leguminous plants, was prescribed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Zhenhua, Chen, Chenkai, Zhu, Yue, Shang, Erxin, Zhao, Ming, Guo, Sheng, Guo, Jianming, Qian, Dawei, Tang, Zhishu, Yan, Hui, Duan, Jinao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384605/ https://www.ncbi.nlm.nih.gov/pubmed/30696059 http://dx.doi.org/10.3390/molecules24030460

Ejemplares similares

Simultaneous Determination of Five Components in Rat Plasma by UPLC–MS/MS and Its Application to a Comparative Pharmacokinetic Study in Baihe Zhimu Tang and Zhimu Extract
por: Li, Guolong, et al.
Publicado: (2015)

Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat
por: Tang, Zhishu, et al.
Publicado: (2015)

Xiexin Tang improves the symptom of type 2 diabetic rats by modulation of the gut microbiota
por: Wei, Xiaoyan, et al.
Publicado: (2018)

Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway
por: Su, Shulan, et al.
Publicado: (2015)

Corrigendum: Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway
por: Su, Shulan, et al.
Publicado: (2015)

Sanhuang Xiexin Tang Ameliorates Type 2 Diabetic Rats via Modulation of the Metabolic Profiles and NF-κB/PI-3K/Akt Signaling Pathways
por: Wei, Xiaoyan, et al.
Publicado: (2018)

Altered Cytokine Gene Expression in Peripheral Blood Monocytes across the Menstrual Cycle in Primary Dysmenorrhea: A Case-Control Study
por: Ma, Hongyue, et al.
Publicado: (2013)

Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats
por: Cai, Hong-Die, et al.
Publicado: (2016)

Preparation, Characterization and Pharmacokinetic Study of Xiangfu Siwu Decoction Essential Oil/β-Cyclodextrin Inclusion Complex
por: Xi, Junzuan, et al.
Publicado: (2015)

Discovery of Quality Markers of Nucleobases, Nucleosides, Nucleotides and Amino Acids for Chrysanthemi Flos From Different Geographical Origins Using UPLC–MS/MS Combined With Multivariate Statistical Analysis
por: Chang, Xiangwei, et al.
Publicado: (2021)

UPLC-QTOF-MS with chemical profiling approach for rapidly evaluating chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction
por: Shang, Erxin, et al.
Publicado: (2012)

Resveratrol is Neuroprotective and Improves Cognition in Pentylenetetrazole-kindling Model of Epilepsy in Rats
por: Meng, X. J., et al.
Publicado: (2014)

Retrieval-Induced Forgetting in a Pentylenetetrazole-Induced Epilepsy Model in the Rat
por: Almahozi, Ahmad, et al.
Publicado: (2018)

Investigating Cardiac Morphological Alterations in a Pentylenetetrazol-Kindling Model of Epilepsy
por: Akyuz, Enes, et al.
Publicado: (2020)

Comparative Pharmacokinetics of three major bioactive components in rats after oral administration of Typhae Pollen-Trogopterus Feces drug pair before and after compatibility
por: Zeng, Huiting, et al.
Publicado: (2016)

Comparative Analysis of the Major Chemical Constituents in Salvia miltiorrhiza Roots, Stems, Leaves and Flowers during Different Growth Periods by UPLC-TQ-MS/MS and HPLC-ELSD Methods
por: Zeng, Huiting, et al.
Publicado: (2017)

Characteristic and Mechanism of Drug-Herb Interaction Between Acetylsalicylic Acid and Danhong Injection Mediated by Organic Anion Transporters
por: Li, Jianping, et al.
Publicado: (2020)

Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
por: Amada, Naoki, et al.
Publicado: (2013)

Enhanced Astrocyte Activity and Excitatory Synaptic Function in the Hippocampus of Pentylenetetrazole Kindling Model of Epilepsy
por: Díaz, Franco, et al.
Publicado: (2023)

AmberTools
por: Case, David A., et al.
Publicado: (2023)

Anti-kindling effect of Ginkgo biloba leaf extract and L-carnitine in the pentylenetetrazol model of epilepsy
por: Essawy, Amina E., et al.
Publicado: (2022)

Pentylenetetrazole kindling-induced epilepsy rat models: Insight on the severity state, a comparative study
por: Ngoupaye, Gwladys Temkou, et al.
Publicado: (2022)

A comparative study to optimize experimental conditions of pentylenetetrazol and pilocarpine-induced epilepsy in zebrafish larvae
por: Szep, David, et al.
Publicado: (2023)

Comparisons of the Pharmacokinetic Profile of Four Bioactive Components after Oral Administration of Gan-Sui-Ban-Xia Decoction Plus-Minus Gansui and Gancao Drug Combination in Normal Rats
por: Zhang, Yang, et al.
Publicado: (2015)

Anticonvulsant Action and Long-Term Effects of Chronic Cannabidiol Treatment in the Rat Pentylenetetrazole-Kindling Model of Epilepsy
por: Gáll, Zsolt, et al.
Publicado: (2022)

Effects of Rosmarinus officinalis L. Extract on Neurobehavioral and Neurobiological Changes in Male Rats with Pentylenetetrazol-Induced Epilepsy
por: Alrashdi, Jawaher, et al.
Publicado: (2023)

Anticonvulsant Effects of Dingxian Pill in Pentylenetetrazol-Kindled Rats
por: Zhu, Yudan, et al.
Publicado: (2019)

Processing of Kansui Roots Stir-Baked with Vinegar Reduces Kansui-Induced Hepatocyte Cytotoxicity by Decreasing the Contents of Toxic Terpenoids and Regulating the Cell Apoptosis Pathway
por: Yan, Xiaojing, et al.
Publicado: (2014)

Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production
por: Wang, Yingyi, et al.
Publicado: (2020)

Comparative Characterization of Total Flavonol Glycosides and Terpene Lactones at Different Ages, from Different Cultivation Sources and Genders of Ginkgo biloba Leaves
por: Yao, Xin, et al.
Publicado: (2012)

Network-Based Biomarkers for Cold Coagulation Blood Stasis Syndrome and the Therapeutic Effects of Shaofu Zhuyu Decoction in Rats
por: Su, Shulan, et al.
Publicado: (2013)

Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy
por: Erdogan, Mumin Alper, et al.
Publicado: (2018)

Therapeutic Effects of Oleuropein in Improving Seizure, Oxidative Stress and Cognitive Disorder in Pentylenetetrazole Kindling Model of Epilepsy in Mice
por: Asgharzade, Samira, et al.
Publicado: (2020)

AmberMDrun: A Scripting Tool for Running Amber MD in an Easy Way
por: Zhang, Zhi-Wei, et al.
Publicado: (2023)

Available sustainable alternatives replace endangered animal horn based on their proteomic analysis and bio-effect evaluation
por: Liu, Rui, et al.
Publicado: (2016)

Amber waves American clarinet music.
Publicado: (1996)

Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism
por: Ma, Yingchang, et al.
Publicado: (2016)

Modulation of P2X Purinoceptor 3 (P2X3) in Pentylenetetrazole-Induced Kindling Epilepsy in Rats
por: Xia, Jie, et al.
Publicado: (2018)

Syntaxin 1B Mediates Berberine’s Roles in Epilepsy-Like Behavior in a Pentylenetetrazole-Induced Seizure Zebrafish Model
por: Zheng, Yang-Min, et al.
Publicado: (2018)

Toxic Peptide From Palythoa caribaeorum Acting on the TRPV1 Channel Prevents Pentylenetetrazol-Induced Epilepsy in Zebrafish Larvae
por: Wang, Xiufen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l5ncbtd9ittd3r0jfd3bcilubi