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Iron(III)-Catalyzed Highly Regioselective Halogenation of 8-Amidoquinolines in Water
A simple protocol of iron(III)-catalyzed halogenation of 8-amidoquinolines in water under mild conditions was developed, affording the 5-halogenlated products in good to excellent yields up to 98%. The reaction mechanism most likely involves a single-electron transfer (SET) process.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384643/ https://www.ncbi.nlm.nih.gov/pubmed/30717184 http://dx.doi.org/10.3390/molecules24030535 |