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P-glycoprotein Inhibitor Tariquidar Potentiates Efficacy of Astragaloside IV in Experimental Autoimmune Encephalomyelitis Mice

ATP-binding cassette (ABC) transporters, such as P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), often reduce drug efficacy and are the major cause of drug resistance. Astragaloside IV (ASIV), one of the bioactive saponins isolated from Astragalus membranaceus, has been demonstrat...

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Detalles Bibliográficos
Autores principales:	Zhang, Wei, Liu, Mei, Yang, Liu, Huang, Fei, Lan, Yunyi, Li, Hongli, Wu, Hui, Zhang, Beibei, Shi, Hailian, Wu, Xiaojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384695/ https://www.ncbi.nlm.nih.gov/pubmed/30717494 http://dx.doi.org/10.3390/molecules24030561

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