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Transthyretin Amyloid Fibril Disrupting Activities of Extracts and Fractions from Juglans mandshurica Maxim. var. cordiformis (Makino) Kitam.
Transthyretin-related amyloidosis is a slowly progressive disorder caused by deposition of insoluble amyloid plaques formed by fibrillization of mutant or defective transthyretin (TTR) monomers that leads to neurodegeneration and organ failure. Thus, any compound exhibiting TTR amyloid formation inh...
Autores principales: | Chaudhary, Niraj, Sasaki, Ryoko, Shuto, Tsuyoshi, Watanabe, Masato, Kawahara, Teppei, Suico, Mary Ann, Yokoyama, Takeshi, Mizuguchi, Mineyuki, Kai, Hirofumi, Devkota, Hari Prasad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384717/ https://www.ncbi.nlm.nih.gov/pubmed/30704121 http://dx.doi.org/10.3390/molecules24030500 |
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