Retro-1-Oligonucleotide Conjugates. Synthesis and Biological Evaluation

Addition of small molecule Retro-1 has been described to enhance antisense and splice switching oligonucleotides. With the aim of assessing the effect of covalently linking Retro-1 to the biologically active oligonucleotide, three different derivatives of Retro-1 were prepared that incorporated a ph...

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Detalles Bibliográficos
Autores principales: Agramunt, Jordi, Pedroso, Enrique, Kreda, Silvia M., Juliano, Rudolph L., Grandas, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384773/
https://www.ncbi.nlm.nih.gov/pubmed/30736307
http://dx.doi.org/10.3390/molecules24030579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384773/
https://www.ncbi.nlm.nih.gov/pubmed/30736307
http://dx.doi.org/10.3390/molecules24030579

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