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Microwave-Assisted Synthesis of Mono- and Disubstituted 4-Hydroxyacetophenone Derivatives via Mannich Reaction: Synthesis, XRD and HS-Analysis

An efficient microwave-assisted one-step synthetic route toward Mannich bases is developed from 4-hydroxyacetophenone and different secondary amines in quantitative yields, via a regioselective substitution reaction. The reaction takes a short time and is non-catalyzed and reproducible on a gram sca...

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Detalles Bibliográficos
Autores principales:	Aljohani, Ghadah, Said, Musa A., Lentz, Dieter, Basar, Norazah, Albar, Arwa, Alraqa, Shaya Y., Ali, Adeeb Al-Sheikh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384783/ https://www.ncbi.nlm.nih.gov/pubmed/30736403 http://dx.doi.org/10.3390/molecules24030590

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