Cargando…
Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands
G-quadruplexes are four-stranded nucleic acids structures that can form in guanine-rich sequences. Following the observation that G-quadruplexes are particularly abundant in genomic regions related to cancer, such as telomeres and oncogenes promoters, several G-quadruplex-binding molecules have been...
Autores principales: | Pirota, Valentina, Nadai, Matteo, Doria, Filippo, Richter, Sara N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384834/ https://www.ncbi.nlm.nih.gov/pubmed/30682828 http://dx.doi.org/10.3390/molecules24030426 |
Ejemplares similares
-
Selective Binding and Redox-Activity on Parallel G-Quadruplexes by Pegylated Naphthalene Diimide-Copper Complexes
por: Pirota, Valentina, et al.
Publicado: (2021) -
Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography
por: Platella, Chiara, et al.
Publicado: (2020) -
G-Quadruplex
DNA as a Target in Pathogenic
Bacteria: Efficacy of an Extended Naphthalene Diimide Ligand and Its
Mode of Action
por: Cebrián, Rubén, et al.
Publicado: (2021) -
The Oncogenic Signaling Pathways in BRAF-Mutant Melanoma Cells Are Modulated by Naphthalene Diimide-Like G-Quadruplex Ligands
por: Recagni, Marta, et al.
Publicado: (2019) -
Synthesis, Binding
and Antiviral Properties of Potent
Core-Extended Naphthalene Diimides Targeting the HIV-1 Long
Terminal Repeat Promoter G-Quadruplexes
por: Perrone, Rosalba, et al.
Publicado: (2015)