Drug Sensitivity Screening and Targeted Pathway Analysis Reveal a Multi-Driver Proliferative Mechanism and Suggest a Strategy of Combination Targeted Therapy for Colorectal Cancer Cells

Treatment of colorectal cancer mostly relies on traditional therapeutic approaches, such as surgery and chemotherapy. Limited options of targeted therapy for colorectal cancer narrowly focus on blocking cancer-generic targets VEGFR and EGFR. Identifying the oncogenic drivers, understanding their con...

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Detalles Bibliográficos
Autores principales: Shen, Jinyan, Li, Li, Yang, Tao, Cheng, Niuliang, Sun, Gongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384902/
https://www.ncbi.nlm.nih.gov/pubmed/30754629
http://dx.doi.org/10.3390/molecules24030623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384902/
https://www.ncbi.nlm.nih.gov/pubmed/30754629
http://dx.doi.org/10.3390/molecules24030623

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