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Mutations in sigma 70 transcription factor improves expression of functional eukaryotic membrane proteins in Escherichia coli
Eukaryotic integral membrane proteins (IMPs) are difficult to study due to low functional expression levels. To investigate factors for efficient biogenesis of eukaryotic IMPs in the prokaryotic model organism Escherichia coli, important, e.g., for isotope-labeling for NMR, we selected for E. coli c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384906/ https://www.ncbi.nlm.nih.gov/pubmed/30792443 http://dx.doi.org/10.1038/s41598-019-39492-9 |