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Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer

BACKGROUND: The RAS/RAF/MEK/ERK and PI3K/AKT/mTOR signaling pathways all belong to mitogen-activated protein kinase (MAPK) signaling pathways, Mutations in any one of the upstream genes (such as the RAS gene or the BRAF gene) may be transmitted to the protein through transcription or translation, re...

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Detalles Bibliográficos
Autores principales:	Wan, Xiang-Bin, Wang, Ai-Qin, Cao, Jian, Dong, Zhi-Chuang, Li, Ning, Yang, Sen, Sun, Miao-Miao, Li, Zhi, Luo, Su-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2019
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385012/ https://www.ncbi.nlm.nih.gov/pubmed/30809081 http://dx.doi.org/10.3748/wjg.v25.i7.808

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