Cargando…
Novel Bispecific Aptamer Enhances Immune Cytotoxicity Against MUC1-Positive Tumor Cells by MUC1-CD16 Dual Targeting
A promising strategy in cancer immunotherapy is the employment of a bispecific agent that can bind with both tumor markers and immunocytes for recruitment of lymphocytes to tumor sites and enhancement of anticancer immune reactions. Mucin1 (MUC1) is a tumor marker overexpressed in almost all adenoca...
Autores principales: | Li, Zhaoyi, Hu, Yan, An, Yacong, Duan, Jinhong, Li, Xundou, Yang, Xian-Da |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385031/ https://www.ncbi.nlm.nih.gov/pubmed/30699986 http://dx.doi.org/10.3390/molecules24030478 |
Ejemplares similares
-
Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro
por: Hu, Yan, et al.
Publicado: (2012) -
Targeted Therapy of Colon Cancer by Aptamer-Guided Holliday Junctions Loaded with Doxorubicin
por: Yao, Fengjiao, et al.
Publicado: (2020) -
Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells
por: An, Yacong, et al.
Publicado: (2019) -
Suppression of MUC1-Overexpressing Tumors by a Novel MUC1/CD3 Bispecific Antibody
por: Fang, Jun, et al.
Publicado: (2023) -
Novel Complex of PD-L1 Aptamer and Albumin Enhances Antitumor Efficacy In Vivo
por: An, Yacong, et al.
Publicado: (2022)