20-Hydroxy-3-Oxolupan-28-Oic Acid Attenuates Inflammatory Responses by Regulating PI3K–Akt and MAPKs Signaling Pathways in LPS-Stimulated RAW264.7 Macrophages

20-Hydroxy-3-oxolupan-28-oic acid (HOA), a lupane-type triterpene, was obtained from the leaves of Mahonia bealei, which is described in the Chinese Pharmacopeia as a remedy for inflammation and related diseases. The anti-inflammatory mechanisms of HOA, however, have not yet been fully elucidated. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Yufeng, Li, Fu, Luo, Yanyan, Zhang, Liang, Lu, Shuya, Xing, Rui, Yan, Bingjun, Zhang, Hongyin, Hu, Weicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385096/
https://www.ncbi.nlm.nih.gov/pubmed/30678231
http://dx.doi.org/10.3390/molecules24030386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385096/
https://www.ncbi.nlm.nih.gov/pubmed/30678231
http://dx.doi.org/10.3390/molecules24030386

Ejemplares similares