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20-Hydroxy-3-Oxolupan-28-Oic Acid Attenuates Inflammatory Responses by Regulating PI3K–Akt and MAPKs Signaling Pathways in LPS-Stimulated RAW264.7 Macrophages

20-Hydroxy-3-oxolupan-28-oic acid (HOA), a lupane-type triterpene, was obtained from the leaves of Mahonia bealei, which is described in the Chinese Pharmacopeia as a remedy for inflammation and related diseases. The anti-inflammatory mechanisms of HOA, however, have not yet been fully elucidated. T...

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Detalles Bibliográficos
Autores principales:	Cao, Yufeng, Li, Fu, Luo, Yanyan, Zhang, Liang, Lu, Shuya, Xing, Rui, Yan, Bingjun, Zhang, Hongyin, Hu, Weicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385096/ https://www.ncbi.nlm.nih.gov/pubmed/30678231 http://dx.doi.org/10.3390/molecules24030386

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