Cargando…

Design, Synthesis, and Biological Activities of Novel 1,3,5-Trimethylpyrazole-Containing Malonamide Derivatives

New 1,3,5-trimethylpyrazole-containing malonamide derivatives based on pyflubumide were designed, synthesized, and characterized using (1)H-NMR, (13)C-NMR, and high-resolution mass spectra (HRMS). The results of preliminary bioassays showed that the target compounds possessed good activities against...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qi-Bo, Liao, Min, Liu, Qing, Feng, Tong, Xu, Zhi-Yuan, Rui, Chang-Hui, Liu, Shang-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385117/ https://www.ncbi.nlm.nih.gov/pubmed/30717498 http://dx.doi.org/10.3390/molecules24030562

Ejemplares similares

Design and Synthesis of Malonamide Derivatives as Antibiotics against Methicillin-Resistant Staphylococcus aureus
por: Su, Jung-Chen, et al.
Publicado: (2017)

Facile synthesis and nematicidal activity evaluation of thiophosphinyl amide [(Pz)(2)P(S)NHR] and thiophosphonyl diamide [(Pz)P(S)(NHR)(2)] (Pz = 1,3,5-trimethylpyrazole, R = biphenyl derivatives)
por: Chen, Xiao, et al.
Publicado: (2021)

Trimethylpyrazole: a simple heterocycle reflecting Kitaigorodskii’s packing principle
por: van Terwingen, Steven, et al.
Publicado: (2022)

N,N′-Bis(3-chlorophenyl)malonamide
por: Rodrigues, Vinola Z., et al.
Publicado: (2011)

Synthesis, Crystal Structure and DFT Studies of a New Dinuclear Ag(I)-Malonamide Complex
por: Soliman, Saied M., et al.
Publicado: (2018)

Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
por: Purgatorio, Rosa, et al.
Publicado: (2022)

Design, Synthesis, and Anti-PVY Biological Activity of 1,3,5-Triazine Derivatives Containing Piperazine Structure
por: Bai, Lian, et al.
Publicado: (2023)

Design, synthesis and biological activities of echinopsine derivatives containing acylhydrazone moiety
por: Cui, Peipei, et al.
Publicado: (2022)

Synthesis, Characterization, and Biological Evaluations of 1,3,5-Triazine Derivatives of Metformin Cyclization with Berberine and Magnolol in the Presence of Sodium Methylate
por: Cao, Han, et al.
Publicado: (2017)

Synthesis, Characterization and Biological Evaluation of Magnolol and Honokiol Derivatives with 1,3,5-Triazine of Metformin Cyclization
por: Ren, Cui, et al.
Publicado: (2020)

Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups
por: Wang, Qi, et al.
Publicado: (2022)

Novel (E)-β-Farnesene Analogues Containing 2-Nitroiminohexahydro-1,3,5-triazine: Synthesis and Biological Activity Evaluation
por: Qin, Yaoguo, et al.
Publicado: (2016)

Design, synthesis and antimicrobial activities of novel 1,3,5-thiadiazine-2-thione derivatives containing a 1,3,4-thiadiazole group
por: Yan, Jinghua, et al.
Publicado: (2019)

Design, Synthesis and Biological Evaluation of Benzohydrazide Derivatives Containing Dihydropyrazoles as Potential EGFR Kinase Inhibitors
por: Wang, Hai-Chao, et al.
Publicado: (2016)

Design, Synthesis and Biological Evaluation of 1,3,5-Triazine Derivatives Targeting hA(1) and hA(3) Adenosine Receptor
por: Park, Sujin, et al.
Publicado: (2022)

Design, Synthesis, and Biological Evaluation of Novel Nitrogen Heterocycle-Containing Ursolic Acid Analogs as Antitumor Agents
por: Wang, Wenzhi, et al.
Publicado: (2019)

Design, synthesis, biological evaluation and molecular docking study of novel pleuromutilin derivatives containing substituted benzoxazole as antibacterial agents
por: Ren, Jie, et al.
Publicado: (2023)

Design, Synthesis, and Biological Activity of Novel Chalcone Derivatives Containing an 1,2,4-Oxadiazole Moiety
por: Luo, Ling, et al.
Publicado: (2022)

Synthesis and Preliminary Biological Evaluation of 1,3,5-Triazine Amino Acid Derivatives to Study Their MAO Inhibitors
por: Khattab, Sherine N., et al.
Publicado: (2015)

Design, Synthesis, and Biological Evaluation of New Azulene-Containing Chalcones
por: Bala, Daniela, et al.
Publicado: (2022)

Novel Fluorinated 7-Hydroxycoumarin Derivatives Containing an Oxime Ether Moiety: Design, Synthesis, Crystal Structure and Biological Evaluation
por: Wang, Qing-Qing, et al.
Publicado: (2021)

Shock-Induced Hot Spot Formation and Spalling in 1,3,5-trinitroperhydro-1,3,5-triazine Containing a Cube Void
por: Zhang, Yaping, et al.
Publicado: (2019)

Design and Synthesis of New 1,3,5‐Trisubstituted Triazines for the Treatment of Cancer and Inflammation
por: Zacharie, Boulos, et al.
Publicado: (2018)

Selective Synthesis of N-[1,3,5]Triazinyl-α-Ketoamides and N-[1,3,5]Triazinyl-Amides from the Reactions of 2-Amine-[1,3,5]Triazines with Ketones
por: Li, Yue, et al.
Publicado: (2023)

Design, Synthesis, Antifungal Activity, and Molecular Docking of Streptochlorin Derivatives Containing the Nitrile Group
por: Liu, Jing-Rui, et al.
Publicado: (2023)

o-Carboranylalkoxy-1,3,5-Triazine Derivatives: Synthesis, Characterization, X-ray Structural Studies, and Biological Activity
por: Jin, Guo Fan, et al.
Publicado: (2018)

Design, Synthesis and Biological Evaluation of Novel Thienylpyridyl- and Thioether-Containing Acetamides and Their Derivatives as Pesticidal Agents
por: Li, Huan, et al.
Publicado: (2021)

Design, Synthesis and Biological Evaluation of Novel 1,3,5-Triazines: Effect of Aromatic Ring Decoration on Affinity to 5-HT(7) Receptor
por: Kułaga, Damian, et al.
Publicado: (2022)

Catalyst-free synthesis of tetrahydropyrimidines via formal [3+3]-cycloaddition of imines with 1,3,5-hexahydro-1,3,5-triazines
por: Chen, Long, et al.
Publicado: (2018)

Complexes With Biologically Active Ligands. Part 7(1) Synthesis and Fungitoxic Activity of Metal Complexes Containing 1,3,5-tris-(8-Hydroxyquinolino)- Trichlorocyclo-Triphosphazatriene
por: Barboiu, Mihai, et al.
Publicado: (1996)

An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids
por: Jansa, Petr, et al.
Publicado: (2012)

Synthesis and Biological Activity of Myricetin Derivatives Containing Pyrazole Piperazine Amide
por: Liu, Fang, et al.
Publicado: (2023)

Biguanide-Based Synthesis of 1,3,5-Triazine Derivatives with Anticancer Activity and 1,3,5-Triazine Incorporated Calcium Citrate Nanoparticles
por: Chalermnon, Monnaya, et al.
Publicado: (2021)

Design, Synthesis, and Bioactivity of Chalcone Derivatives Containing Indanone
por: Sun, Nan, et al.
Publicado: (2023)

Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
por: Zhang, Shu-Guang, et al.
Publicado: (2018)

Discovery of Novel Thiosemicarbazides Containing 1,3,5-Triazines Derivatives as Potential Synergists against Fluconazole-Resistant Candida albicans
por: Xie, Fei, et al.
Publicado: (2022)

Synthesis and photo-physical properties of fluorescent 1,3,5-triazine styryl derivatives
por: Padalkar, Vikas S, et al.
Publicado: (2011)

Synthesis and biological activity of myricetin derivatives containing 1,3,4-thiadiazole scaffold
por: Zhong, Xinmin, et al.
Publicado: (2017)

Synthesis, Structures and Electrochemical Properties of Lithium 1,3,5-Benzenetricarboxylate Complexes
por: Cheng, Pei-Chi, et al.
Publicado: (2019)

Synthesis of Novel Benzodifuranyl; 1,3,5-Triazines; 1,3,5-Oxadiazepines; and Thiazolopyrimidines Derived from Visnaginone and Khellinone as Anti-Inflammatory and Analgesic Agents
por: Abu-Hashem, Ameen Ali, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ak65ukgr1uje4p1hdjuuq2obup